{
  "schemaVersion": 1,
  "language": "en",
  "contentUpdated": "2026-09-06",
  "publisher": "Biocurrent, Inc.",
  "canonicalUrl": "https://biocurrent.com/research/",
  "kind": "company-reported aggregate summary; not participant-level data",
  "platform": {
    "researchFocus": "Chronic pain",
    "description": "Biocurrent is developing an investigational closed-loop bioelectronic system for chronic pain research. AI analyzes EEG feedback to optimize the alternating current (AC) delivered through skin-surface electrodes.",
    "closedLoop": "The EEG signal provides feedback on the user’s brain activity. AI analyzes that signal and adjusts the delivered electrical current in response. Continuing EEG feedback informs further current adjustments, closing the loop.",
    "delivery": "The investigational system delivers alternating current (AC) through electrodes on the skin near the spine or the area of chronic pain. This is electrical stimulation, not an audio or listening therapy."
  },
  "regulatory": {
    "status": "Investigational",
    "fdaCleared": false,
    "fdaApproved": false,
    "availableForCommercialSale": false
  },
  "context": "Investigational research. Safety and effectiveness have not been established. The system is not FDA-cleared or approved and is not available for commercial sale.",
  "participants": {
    "total": 280,
    "active": 190,
    "control": 90
  },
  "reportedSessions": 697,
  "sessionsPerParticipant": {
    "minimum": 1,
    "maximum": 3,
    "durationMinutes": 30
  },
  "location": "Puerto Vallarta, Mexico",
  "source": "Company-provided summary reproduced on the prior company website. Not a peer-reviewed publication.",
  "limitations": "No public registry identifier or peer-reviewed publication is linked in this summary. The source is the company-provided summary reproduced on the prior company website. Contact the study team for the protocol, analysis plan, registration information, ethics documentation, and publication status. These files contain the same public company-reported information and limitations shown here. They contain aggregate figures only, no participant records, and are not the underlying participant-level study data or a peer-reviewed publication. One center, short observation. Does not establish effectiveness, durability, a cure, or long-term safety.",
  "recruitment": "The investigational system is not available for commercial sale. This website does not enroll participants and does not confirm current recruitment. The contact form is for company and research inquiries.",
  "outcomes": [
    {
      "outcome": "Baseline pain score (0–10)",
      "active": 6.28,
      "control": 6,
      "unit": "NRS 0–10"
    },
    {
      "outcome": "First-session mean reduction",
      "active": 68.3,
      "control": 33.5,
      "unit": "percent"
    },
    {
      "outcome": "Cumulative mean reduction",
      "active": 84,
      "control": 51.7,
      "unit": "percent"
    },
    {
      "outcome": "Final mean pain score (0–10)",
      "active": 0.99,
      "control": 3,
      "unit": "NRS 0–10"
    },
    {
      "outcome": "Participants with ≥50% cumulative reduction",
      "active": 93.2,
      "control": 57.8,
      "unit": "percent"
    },
    {
      "outcome": "Participants reporting a final pain score of zero",
      "active": 51.1,
      "control": 17.8,
      "unit": "percent"
    },
    {
      "outcome": "Reported device-related adverse events",
      "active": 0,
      "control": 0,
      "unit": "count"
    }
  ]
}